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iMedical Apps: Prevention TaskForce

Med Page Today - May 29, 2020 - 3:00pm
]]>(MedPage Today) -- The Prevention TaskForce app (formerly ePSS) is an application designed and developed by the Agency for Healthcare Research and Quality (AHRQ), the nation's lead federal agency for research on healthcare quality, costs, outcomes...

'This Is Not the End of the Story': What We Heard This Week

Med Page Today - May 29, 2020 - 2:30pm
]]>(MedPage Today) -- "This is not the end of the story for the inflammatory hypothesis in mood disorders." -- Muhammad Ishrat Husain, MD, of the Centre for Addiction and Mental Health in Toronto on NSAIDs' failure to improve bipolar depression...

What We've Learned About Our Most Deadly Enemy

Med Page Today - May 29, 2020 - 2:15pm
]]>(MedPage Today) -- With the U.S. recently passing the milestone of 100,000 deaths from COVID-19, MedPage Today Editor-in-Chief Martin Makary, MD, of Johns Hopkins University, speaks with MedPage Today's Director of Video Greg Laub, to discuss the...

Trump Takes U.S. Out of World Health Organization

Med Page Today - May 29, 2020 - 2:00pm
]]>(MedPage Today) -- WASHINGTON -- President Trump on Friday made good on previous threats to leave the World Health Organization, ramping up his criticisms of China as well. At an afternoon press conference, Trump said China's "cover-up" of the...

Could Savolitinib Have a Role in MET-Driven Papillary RCC?

Med Page Today - May 29, 2020 - 1:45pm
]]>(MedPage Today) -- In patients with MET-driven papillary renal cell carcinoma (RCC), treatment with an investigational MET inhibitor yielded similar survival outcomes as the current standard, and with higher rates of response and an improved safety...

Acute Kidney Injury Seen in Most Severe COVID-19 Cases

Med Page Today - May 29, 2020 - 1:30pm
]]>(MedPage Today) -- New data from two health systems in New York City -- where hospitals struggled to keep up with dialysis demands as they were flooded with COVID-19 patients -- detailed a high rate of acute kidney injury among infected patients...

Air Quality Tied to MS Risk

Med Page Today - May 29, 2020 - 1:15pm
]]>(MedPage Today) -- Italians residing in areas with high air pollution levels had a significantly greater risk of developing multiple sclerosis (MS) than those who lived in areas with cleaner air, researchers said. MS risk was 29% higher among...

'Superpotent' Thyroid Drug Recall; 10% of Hospitalized COVID-19 Patients With Diabetes Die

Med Page Today - May 29, 2020 - 1:00pm
]]>(MedPage Today) -- The FDA announced that Acella Pharmaceuticals issued a voluntary recall of 13 lots of the company's 30-mg, 60-mg, and 90-mg NP Thyroid tablets for being "superpotent" -- i.e., containing as much as 115% of the labeled amount...

FOURIER Confirms PCSK9 Inhibitor Lowers Heart Attack Risk

Med Page Today - May 29, 2020 - 12:30pm
(MedPage Today) -- Study Authors: Stephen D. Wiviott, Robert P. Giugliano, et al.; Glenn N. Levine Target Audience and Goal Statement: Cardiologists, primary care physicians The goal of this study was to assess the types and sizes of myocardial...

Alzheimer's Markers Altered With Cancer Drug

Med Page Today - May 29, 2020 - 12:00pm
]]>(MedPage Today) -- The leukemia drug nilotinib (Tasigna) showed hints that it may have disease-modifying benefits in Alzheimer's disease. In a phase II study, the drug appeared to be well-tolerated in Alzheimer's patients but showed more adverse...

Enhertu Impresses in HER2-Positive Gastric Cancer

Med Page Today - May 29, 2020 - 11:30am
]]>(MedPage Today) -- Pretreated gastric cancer patients with HER2-positive disease had significantly improved rates of response and survival with trastuzumab deruxtecan (Enhertu) rather than chemotherapy, an open-label phase II trial showed. Among...

FDA OKs 3-Drug Combo to Reduce Heavy Menstrual Bleeding

Med Page Today - May 29, 2020 - 11:00am
]]>(MedPage Today) -- WASHINGTON -- A triple hormonal combination product won FDA approval Friday to manage heavy menstrual bleeding associated with uterine fibroids in premenopausal women. To be sold as Oriahnn and made by AbbVie, the product...

First-Line Win for Anti-PD-1 Drug in Advanced Colon Cancer

Med Page Today - May 29, 2020 - 10:30am
]]>(MedPage Today) -- Patients with untreated heavily mutated metastatic colorectal cancer (mCRC) lived twice as long without disease progression when they received an immune checkpoint inhibitor instead of chemotherapy, a randomized trial showed...

Med School to Students: Sign This COVID Waiver or Risk Graduation Delay

Med Page Today - May 29, 2020 - 10:00am
]]>(MedPage Today) -- The University of South Carolina School of Medicine Greenville is asking students to sign a waiver acknowledging risk and absolving the school of liability before starting their next clinical rotation, officials confirmed to...

Ethics Consult: Compel Woman to Have C-Section? MD/JD Bangs Gavel

Med Page Today - May 29, 2020 - 9:30am
]]>(MedPage Today) -- Welcome to Ethics Consult -- an opportunity to discuss, debate (respectfully), and learn together. We select an ethical dilemma in patient care, you vote, and then we present an expert's judgment. Last week, you voted on the...

OncMadness 2020 Championship Match

Med Page Today - May 29, 2020 - 9:00am
]]>(MedPage Today) -- We've made it to the OncMadness 2020 Championship Round. See if you picked the Blue Ribbon Panel's ultimate champion! Regions: Immune and Cellular Tx versus Health Policy Matchup Checkpoint inhibition...

NDMA Prompts Metformin Recall

Med Page Today - May 29, 2020 - 8:30am
]]>(MedPage Today) -- Higher-than-acceptable levels of the nitrosamine impurity N-nitrosodimethylamine (NDMA) were detected in certain metformin products used to treat type 2 diabetes, the FDA announced on Thursday. NDMA, a genotoxic substance and...

Hazy on Ground-Glass Opacities? Here's What They Are

Med Page Today - May 29, 2020 - 8:00am
]]>(MedPage Today) -- The COVID-19 pandemic has brought radiologists' penchant for descriptive terms front-and-center, with frequent references to one feature in particular: ground-glass opacities. The term refers to the hazy, white-flecked pattern...

'Sniff Test' Predicts Return of Consciousness After Brain Injury

Med Page Today - May 29, 2020 - 7:30am
(MedPage Today) -- Study Authors: Anat Arzi, Liron Rozenkrantz, et al. Target Audience and Goal Statement: Critical care providers, hospitalists, neurologists The goal of this study was to determine whether the sniff test -- a non-verbal non...

Clinical Challenge: Diagnosing Ulcerative Colitis

Med Page Today - May 29, 2020 - 7:00am
]]>(MedPage Today) -- Recent years have seen a proliferation of effective targeted treatments for ulcerative colitis (UC). But before considering a management plan, the initial steps for a patient who presents with possible UC are clinical and endoscopic...